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jove.com
Video: PI3K/mTOR/AKT Signaling Pathway
4.5K Views. The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). The first form ...
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Cancer starts when normal biological signals in the body go haywire, also known as dysregulation. In breast cancer, one of the most common signals that can go haywire is called PI3K, which controls how cells grow and stay healthy. Learn more from our Lead Medical Director, Jennifer Schutzman who uses everyday objects to explain this critical pathway in breast cancer and efforts to target it more precisely than ever before. Learn more and watch the full video series: https://www.gene.com/stories/
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