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1 in 2,000,000: 46 animals with rare genetic mutations that don’t even look real (new pics)

Genes are short sections of DNA that determine an animal’s traits—everything from coat color and claw strength to body shape ...
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Synthetic RNA 'nanostars' create programmable compartments in bacteria

Researchers at the Department of Chemical Engineering and Biotechnology (CEB) have found a new way to organize molecules ...
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...

Scientists Discover DNA Is Already Organized Before Life Switches On

For many years, researchers believed that the DNA inside a newly fertilized egg began as a structural ‘blank slate’ – a loose ...

Bringing quantum ideas to the messy world of disordered proteins

Imagine trying to design a key for a lock that is constantly changing its shape. That is the exact challenge we face in ...
IEEE

Sequential Linear Programming With Adaptive Linearization Error Limits for All-Time Feasibility

Abstract: This letter presents an enhanced Trust Region Method (TRM) for Sequential Linear Programming (SLP) designed to improve the initial feasible solution to a constrained nonlinear programming ...
GitHub

Python rich client for visual protein Sequence to Structure Analysis (PySSA)

📣 Update details for version 1.3.0 📣 Please reinstall PySSA if your current version is 1.2.0 or older! Version 1.3.0 fixes the bug that every structure ...
IEEE

SCCENet: A Symmetric CNN-Based Model for Channel Estimation in OFDM Systems

Abstract: In deep learning (DL)-based channel estimation for orthogonal frequency-division multiplexing (OFDM) systems, existing feature extraction blocks (FEBlocks) typically adopt a sequential ...
GitHub

PLAID (Protein Latent Induced Diffusion)

PLAID is a multimodal generative model that can generate protein sequence and all-atom structure based on conditional function and taxonomic prompts. Please see our ...