The implementation of distinct gene expression profiles is essential for animal development and physiology. Post-transcriptional silencing by small regulatory RNAs such as miRNAs plays essential roles ...

Donna L. Farber is a professor of surgical sciences, microbiology and immunology at Columbia University Irving Medical Center in New York City, New York, USA. Early in the pandemic, my team spotted ...

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be ...

Tissue optical clearing is a fundamental technique that enhances light penetration deep into biological samples by reducing light scattering through refractive index homogenization. This process ...

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too ...

Theories about how animals became multicellular are shifting as researchers find greater complexity in our single-celled ancestors. From one came many. Some 700 million years ago, a single cell gave ...

3D surface of the fruit fly wing disc before (left) and after (right) eversion. Highlighted in blue is the pouch region, which transforms from a radially symmetric dome into a curved fold by ...