What is the differential diagnosis for a formerly active and healthy 70-year-old woman with worsening proximal weakness, torticollis, and a widespread raised red rash across her cheeks bilaterally?

This report describes a female patient in her 60s with an immune-mediated necrotising myopathy (IMNM) occurring after semaglutide use. She was found to have progressive dysphagia, dysphonia, proximal ...

A 30-year-old African-American woman presented to the emergency department for medical assessment after becoming too weak to walk. She reported proximal muscle aches in both arms and legs, a skin rash ...

Dr. Chidiebere D. Akusobi (Medicine): A 44-year-old woman was evaluated in the rheumatology clinic of this hospital because of proximal muscle weakness and myalgia. The patient had been in her usual ...

Classic DM (CDM) presents with pathognomonic cutaneous findings and progressive, symmetric proximal muscle weakness. Cutaneous disease usually precedes the appearance of myositis by 3–6 months in ...

Mr. M, age 56, arrived in the ER with progressive weakness. Until the fatigue began, he had exercised daily at a gym. Over a two-week period, however, the debility had worsened such that he was unable ...

Dermatomyositis is a rare autoimmune disease that typically affects the skin, muscle and respiratory system. Patients with dermatomyositis usually require prompt treatment with intense ...

On World Rare Disease Day, we take a look at Pompe disease - a rare genetic disorder caused by a deficiency of the GAA enzyme, leading to glycogen buildup in muscles. It results in progressive muscle ...

SMA is a genetic condition that impacts motor neurons, leading to muscle weakness that affects essential functions like breathing and movement. Treatments like Spinraza and Zolgensma can help manage ...

Weakness in the legs can be a sign of serious health issues like stroke or cancer. Symptoms like sudden leg weakness, confusion, and dizziness may mean you need medical help right away. Exercise and ...