Targeting the Insulin-Like Growth Factor (IGF) System Is Not as Simple as Just Targeting the Type 1 IGF Receptor Hedgehog (HH) signaling has been investigated for its role in tumorigenesis because of ...

Investigators have found a known genetic pathway to be active in many difficult-to-treat pediatric brain tumors called low-grade gliomas, potentially offering a new target for the treatment of these ...

Please provide your email address to receive an email when new articles are posted on . Investigators at The University of Texas MD Anderson Children’s Cancer Hospital found that blocking the Notch ...

Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer. Researchers have identified an important signaling pathway ...

A standard proforma was used to retrospectively collect information on demographics, diagnosis, referral pathways, and symptoms of incident pediatric brain tumor cases between January 2018 and October ...

Scientists at St. Jude Children's Research Hospital created a hepatoblastoma (liver cancer) model that more accurately reflects the pathology and genomics of the disease. Research using the model ...

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of ...