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Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity

By Hugo Francisco de Souza Can combining two gut hormone pathways unlock better obesity treatments? In the first human trial ...
Business Wire

Journal of the American Medical Association (JAMA) Publishes Results from First-Ever Randomized, Placebo-Controlled Clinical Trial Assessing the Dose-Dependent Efficacy of ...

The Phase 2b study demonstrated a statistically significant dose-response relationship at the primary endpoint following a single administration of MM120 across four dose levels, with improvements ...
ascopubs.org

Randomized Parallel-Group Phase II Study (NEOTERIC) of Atezolizumab With or Without Tiragolumab After Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Marking Techniques for Target Lymph Nodes in Node-Positive Breast Cancer Treated With Neoadjuvant Therapy in the AXSANA/EUBREAST-03/AGO-B-053 Study This randomized, parallel-group, phase II study ...

iRegene Hits Dual Global Firsts: U.S. Patient Dosed in Phase IIa for NouvNeu001 in Parkinson's and First Enrollment in China's Randomized MSA Trial for NouvNeu004

The global race to treat neurodegenerative diseases has reached a new tempo as iRegene Therapeutics pushes its cell therapy pipeline into key clinical stages in the U.S. and China. Concurrently, the ...
BMJ Global Health

Impact of cooking with liquefied petroleum gas compared with traditional cooking practices on perinatal and early neonatal mortality: the Poriborton cluster randomised ...

Objective To determine whether liquefied petroleum gas (LPG) can reduce perinatal mortality in a setting with high reliance on biomass fuels for cooking.Design Community-based two-arm parallel cluster ...

Bayer’s Finerenone CKD Trial Completion: What Investors Should Watch Next

A positive finerenone readout in non-diabetic CKD would extend Bayer’s cardiorenal franchise beyond current diabetic CKD use, supporting sentiment for BAYRY by opening a broader addressable market. It ...
ascopubs.org

Randomized control trial to validate mitigation of chemotherapy-induced peripheral neuropathy by limb-cooling apparatus in breast cancer patients receiving paclitaxel (CECILIA).

Phase III randomized placebo-controlled trial on repurposing olanzapine for prevention of radiotherapy-induced nausea and vomiting (RINV): CTRI/2022/01/039723. PNQ ≥D 3 months after end of PTX 32.0% ...