Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Scientists have developed injectable "mini livers" that can replicate liver function, potentially buying time for those with liver disease.

More than 10,000 Americans are waiting for a liver transplant. Many more never make the list, because they are too sick to ...

Fats are an important part of the human diet as a major source of energy. Around 90% of the fat stores are on top of muscle, so just under the skin. However, excessive dietary fat intake leads to fat ...

More than 10,000 Americans who suffer from chronic liver disease are on a waitlist for a liver transplant, but there are not ...

Over time, this damages liver cells, triggers inflammation and contributes to fibrosis, which is the build-up of scar tissue. If scarring becomes extensive, it can progress to cirrhosis, a stage where ...