An international team of researchers has discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective ...

Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...

image: A team at the Technical University of Munich (TUM) has induced stem cells to emulate the development of the human heart. The result is a sort of “mini-heart” known as an organoid. It will ...

In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...

Heart attacks scar the heart, leaving patients vulnerable to heart rhythm disorders that can lead to sudden death. While not all who have experienced a cardiac infarction will develop an arrhythmia, ...

Researchers have been using organoids - 3D organ-like, tightly-packed cell cultures - as models to study organ development, disease and drug discovery with excellent success. However, most existing ...

Using a combination for spatial, single-cell transcriptomics and imaging data from 36 hearts, scientists from the KTH Royal Institute of Technology and their collaborators have come up with what they ...

A hole in the heart is a nonmedical term for a type of congenital heart defect. There are many types of holes in the heart, and most are present from birth. Around 1% of babies born in the United ...