Outcomes for patients with clear cell renal cell carcinoma have improved over the past decade due to the approval of immunotherapies, yet still there is a subset of patients who do not respond to this ...

Beta cells (marked in green) in the pancreas are organized in structures termed islets. In most adults, it was found that a subset become senescent and display the marker p16, shown here in red. The ...

The work tests and revises a 50-year old textbook model, known as the Bloch hypothesis, for the evolution of sterol metabolism in eukaryotic cells. The results indicate that the complexity of sterol ...