A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.
A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.
In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...
Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands, scientists are probing a critical question: If ...
Lenacapavir is a multistage, selective inhibitor of HIV-1 capsid function that directly binds to the interface between capsid protein (p24) subunits in hexamers. Surface plasmon resonance sensorgrams ...
Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...
A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.
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